Why do people show different signs of intoxication?
Factors like gender, age, body makeup and health condition affect how intoxicated one can be. For example, a person who drinks on an empty stomach is more likely to get drunk because alcohol easily permeates through.
Several studies suggest that DNA also plays a huge part for people who do not get drunk and have a hangover. But they are more inclined to be alcohol dependent because they do not experience the downsides of consuming too much alcohol.